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EPIPMS project

Laatste wijziging: 24 januari 2022

Epigenetische regulation of myelin basic protein (MBP) in progressive multiple sclerosis (MS)

 

Principal Investigator: dr. Tim Vanmierlo, Researcher: Melissa Schepers

 

The goal of the study is to determine whether the methylation profiles measured in lesions of progressive MS patients are comparable to the profiles found in peripheral blood. This would create the opportunity to identify a new biomarker to facilitate the diagnosis of a progressive MS stadium. Our hypothesis is that meylin basic protein (MBP)-related genes show a changed methylation profile in peripheral blood of progressive MS patients comparted to RRMS patients and healthy controls.